Tlhahisoleseding ea Tlhahiso ea 2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone

Jiangsu Jingye Pharmaceuticale motlotlo ho hlahisa tlaleho e qaqileng ea ts'ebetso ea tlhahiso bakeng sa e 'ngoe ea lik'hemik'hale tsa rona tsa lihlahisoa, 2-Bromo-1-[4-(Methylsulfonyl) Phenyl] -1-Ethanone, e nang le mekhoa e mengata e fapaneng ea metsoako ea meriana.

Selelekela:

2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanone, e tsejoang ka ts'ebeliso ea eona ha ho etsoa metsoako ea carbonyl, ke setsi sa bohlokoahali sa ho etsoa ha meriana e fapaneng, li-API, le lik'hemik'hale tse tloaelehileng. Ka CAS No. ea 50413-24-6 le boima ba molek'hule ea 277.14, motsoako ona o entsoe ka mokhoa o hlokolosi o tiisang boleng bo phahameng le bohloeki.

Mokhoa oa ho kopanya:

The synthesis of2-Bromo-1-[4-(Methylsulfonyl) Phenyl]-1-Ethanonee kenyelletsa mehato e mengata ea bohlokoa:

1. Ts'ebetso ea Ring ea Phenyl: Ts'ebetso e qala ka ts'ebetso ea selikalikoe sa phenyl ho lumella likarabelo tse latelang.

2. Sulfonylation: Ho kenyelletsoa ha sehlopha sa methylsulfonyl ho etsahala ka mokhoa oa ho itšoara ka sulfonylation, ho sebelisa dimethyl sulfate e le moemeli oa sulfonylating.

3. Bromination: Boemo ba alpha ea acetophenone joale bo tlas'a bromination, ho sebelisa bromine e le halogenating agent.

4. Tlhoekiso: Sehlahisoa se tala se kena tšebetsong e matla ea tlhoekiso, ho kenyelletsa le recrystallization le chromatography, ho fihlela boemo bo lakatsehang ba bohloeki.

Netefaletso ea boleng:

Sehlahisoa sa rona se hlahella 'marakeng ka lebaka la boleng ba sona bo holimo, bo tšehelitsoe ke mehato e thata ea taolo ea boleng. Sehlopha se seng le se seng se lekoa ho netefatsa hore se kopana le litekanyetso tsa rona tse phahameng tsa bohloeki le botsitso.

Lisebelisoa:

Motsoako ona o fumana tšebeliso e pharaletseng indastering ea meriana, e sebetsa e le setsi sa ho kopanya metsoako e mengata e sebetsang ea meriana (APIs). Ho feto-fetoha ha eona ho boetse ho etsa hore e tšoanelehe bakeng sa tlhahiso ea tloaelo le lipatlisiso tsa lik'hemik'hale.

Qetello:

At Jiangsu Jingye Pharmaceutical, re ikemiselitse ho fa bareki ba rona lik'hemik'hale tsa boleng bo phahameng tse kang 2-Bromo-1-[4-(Methylsulfonyl) Phenyl] -1-Ethanone. Boinehelo ba rona ho bokhabane bo bonahala ka tlholisano ea litheko tsa rona, ho fana ka thepa ka potlako, le karabelo e potlakileng lipotsong tsa bareki. Bakeng sa tlhaiso-leseling e batsi kapa ho etsa odara, ka kopo.iteanye le rona:imeile:guml@depeichem.com/shiyf@depeichem.com. Re labalabela ho u thusa ka litlhoko tsa hau tsa lik'hemik'hale le tsa meriana.