Likahare tsa Remazolam Benzenesulfonate (CAS No. 308242-23-1)
Mantsoe a tšoanang:(3S) - (7-BroMo-2-oxo-5-pyridin-2-yl-2, 3-dihydro-1H-benzo [e] [1,4] diazepin-3-yl) -propionic acid Methylester; Methyl3-[(3S)-7-bromo-2-oxo-5-(2-pyridinyl)-2, 3-dihydro-1H-1, 4-benzodiazepin-3-yl]propanoate; (S)-Methyl3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate; 3 - [(S) -7-bromo-2-oxo-5-pyridin-2-yl-2, 3-dihydro-1H-1, 4-benzodiazepin-3-yl] -propionicacidmethylester.
Nomoro ea CAS:308242-23-1
Foromo ea molek'hule:C18H16BrN3O3
Boima ba Molek'hule:402.24
Kopo: Meriana, li-intermediates, APIs, tloaelo ea ho kopanya, lik'hemik'hale
Lisebelisoa:Likahare tsa Remazolam Benzenesulfonate
Sebopeho
Bophahamo:Morekisi ea Molemo ka ho Fetisisa, Boleng bo Phahameng, Theko ea Tlholisano, Thomello e potlakileng, karabelo e potlakileng
Lihlopha tse amanang:Lik'hemik'hale Tse Ntle
| Ntho e belang | 545.3±50.0 °C(E boletsoeng esale pele) |
| Botenya | 1.52±0.1 g/cm3(E boletsoeng esale pele) |
| Boemo ba polokelo | E tiisitsoe ka mocheso o omileng, oa Kamore |
| pKa | 11.15±0.70(E boletsoeng esale pele) |
| Litlhaloso tse khethehileng ho latela litlhoko tsa bareki | |
| Ponahalo | Phofo e tšoeu ho isa ho e mosehla |
| Metsi | 1.0% boholo |
| Isomer | 1.5% boholo |
| Bohloeki | 98.0％mets |
Litlhokomelo bakeng sa ho tšoara ka mokhoa o sireletsehileng:
Ho tšoara sebakeng se nang le moea o motle. Apara liaparo tse loketseng tsa tšireletso. Qoba ho kopana le letlalo le mahlo. Qoba ho thehoa ha lerōle le li-aerosols. Sebelisa lisebelisoa tse sa chese. Thibela mollo o bakoang ke mouoane oa electrostatic discharge.
Maemo a polokelo e bolokehileng, ho kenyeletsoa le ho se lumellane hofe kapa hofe:
Boloka setshelo se koetsoe ka thata sebakeng se omeletseng, se pholileng le se nang le moea o motle. Boloka ka thoko ho lijana tsa lijo kapa lisebelisoa tse sa lumellaneng.
Jingye e na le lihlopha tse 86 tsa li-reactor ka kakaretso, tseo palo ea tsona ea enamel e leng 69, ho tloha ho 50 ho isa ho 3000L. Palo ea li-reactors tse sa hloekang ke 18, ho tloha ho 50 ho isa ho 3000L. QC e na le makholo a mefuta eohle ea lisebelisoa tsa tlhahlobo. E ka kopana le tlhahiso ea khoebo le tlhahlobo e felletseng ea sehlahisoa. Sehlahisoa sena ke sehlahisoa sa boemo bo holimo 'me se ka fanoa ho latela litlhoko tsa bareki.
Jiangsu Jingye Pharmaceutical Co., Ltd. e kile ea rehoa Jintan Depei Chemical Co., Ltd. e thehiloeng ka 1994, 'me e fetohela ho moetsi oa meriana ea hloahloa ka 2016. Kamora lilemo tse mashome a mabeli tsa nts'etsopele, Jingye Pharmaceutical e se e holile ho ba setsebi le se felletseng sa lik'hamphani tsa litlama tse fumanehang kantle ho naha le tsa Shanghai, tse kopanyang lihlahisoa tse peli tsa thepa ea kantle le tsa D. Lianyungang.
